Rashford’s return is one of five charges made to the Manchester United from their win over Fulham at the weekend.
And manager Ole Gunnar Solskjaer returns to the line-up he has favoured since taking over.
Jesse Lingard joins Rashford in attack alongside Anthony Martial.
In defence, Ashley Young, Eric Bailly and Victor Lindelof all return.
Alexis Sanchez and Romelu Lukaku are on the bench for United.
Manchester United: De Gea, Young, Lindelof, Bailly, Shaw, Herrera, Matic, Pogba, Lingard, Rashford, Martial.
PSG: Buffon, Kehrer, Silva, Kimpembe, Bernat, Verratti, Marquinhos, Alves, Draxler, Di Maria, Mbappe.
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