A hectic festive fixture list really separates the casual fantasy football managers from the Fantasy Premier League die-hards.
Three rounds of fixtures crammed into seven days creates the opportunity for huge points hauls but missing an FPL deadline could be crucial.
The right captaincy choice can help gaffers maximise any advantage over their rivals, and there are plenty of tempting options to choose from this weekend.
Pierre-Emerick Aubameyang is enjoying heavy investment while Harry Kane has found his stride and Richarlison continues to produce the goods for Everton, but who will you choose to wear the armband in GW16?
Raheem Sterling (Manchester City) vs Chelsea (A)
An unused substitute against Watford, much to the annoyance of thousands of fantasy managers around the world.
Sterling now looks set to return to the starting XI against Chelsea after his midweek rest, and the England international could cause havoc after nine Premier League goals already this season
Pierre-Emerick Aubameyang (Arsenal) vs Huddersfield Town (H)
The Gabon international stole the show in the north London derby with two goals and an assist in the 4-2 win over Tottenham.
Things were a little more low key in a tumultuous match against Manchester United, but there is no reason why Aubameyang cannot be back on the scoresheet at home to Huddersfield.
Marcus Rashford (Manchester United) vs Fulham (H)
Jose Mourinho was full of praise for his attacking trio of Rashford, Jesse Lingard and Anthony Martial after the 2-2 draw with Arsenal.
Rashford was given the nod up front ahead of Romelu Lukaku and a bright display should see the youngster keep his place when the worst defence in the league visits Old Trafford.
Xherdan Shaqiri (Liverpool) vs Bournemouth (A)
Shaqiri has two goals and four assists in his past four matches, having started every one of Liverpool’s matches over that period.
With a crunch Champions League clash with Napoli on the horizon, managers may be better off avoiding the likes of Mohamed Salah and Roberto Firmino in favour of the Swiss international.
Charlie Austin (Southampton) vs Cardiff City (A)
Southampton are under new management after the departure of Mark Hughes and appointment of Ralph Hasenhuttl, and the South Coast club will hope for an immediate boost in results.
Charlie Austin has already found the target against Tottenham for the first goal of the new regime, and the former Burnley man could be set for a productive afternoon against Cardiff.
Richarlison (Everton) vs Watford (H)
The Brazilian has been an undeniably success since his £50million move from Vicarage Road in the summer, scoring seven goals for the Toffees in the Premier League.
The return of Cenk Tosun to the starting XI against Newcastle saw Richarlison pushed out wide but he still managed to find the back of the net and could do once more against his former side.
TOP CHOICE: Harry Kane (Tottenham Hotspur) vs Leicester City (A)
Kane has an outrageous 13 goals in eight appearances against his former side, and is a sure-fire bet to add to that tally this weekend.
The England captain has scored in his last three Premier League appearances and it would take a wise manager to bet against him making it four in a row.